Noscapine (hydrochloride)
Catalogue number:
CAY17255-5 g
Supplier:
Size:
5 g
Product is available in:
£270.00
Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
912-60-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C22H23NO7 • HCl
Molecular Weight:
449.9
Alternative Names:
(3s)-6,7-dimethoxy-3-[(5r)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3h)-isobenzofuranone, monohydrochloride, narcotine, opianine
Product Description:
An alkaloid with anticancer and antitussive activities; binds to tubulin and induces cell cycle arrest at the G2/M phase in HeLa cells at 20 µM; induces apoptosis in HeLa cells and thymocytes (IC50s = 25 and 10 µM, respectively) and reduces proliferation of MCF-7 breast and Renal 1983 bladder cancer cells (IC50s = 42.3 and 39.1 µM, respectively); induces tumor regression in an MCF-7 mouse xenograft model at 120 mg/kg; decreases the number of citric acid-induced coughs in guinea pigs at 30 and 70 mg/kg e
