SMCC
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64987-85-5
≥98%
A solid
C16H18N2O6
334.324
4-[(2,5-
A heterobifunctional cross-linking reagent containing an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins; has been used to cross-link mertansine to an IgG1 monoclonal antibody to form the antibody-drug conjugate DM1-SMCC; immunization of mice with SMCC-coupled keyhole limpet hemocyanin (KLH) antigen and syngeneic splenocytes increases the percentage of proliferating T cells in isolated splenocytes from recipient mice compared to mice immunized with KLH and the adjuvant LPS.




