Anthralin
Catalogue number:
CAY28371-1 g
Supplier:
Size:
1 g
Product is available in:
£46.00
Estimated delivery Thu 4 Jun
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1143-38-0
Purity:
≥90%
Formulation:
A crystalline solid
Molecular Formula:
C14H10O3
Molecular Weight:
226.2274
Alternative Names:
1,8-
Product Description:
An anthrone inhibitor of keratinocyte proliferation and a modulator of differentiation; increases apoptosis and inhibits proliferation of NHKs at 2.5 µM; decreases the mitochondrial membrane potential, increases cytochrome c release, and induces perinuclear mitochondrial clustering in NHKs at 5 µM; decreases β-defensin-2 and S100A9 expression and increases IL-6 and IL-8 expression in IL-17A- and IL-22-stimulated NHKs at 0.25 µM; inhibits A23187-stimulated LTB4 production from human neutrophils (IC50 = 7 µM); induces hair regrowth in a DEBR model of alopecia areata
