Anthralin
Catalogue number:
CAY28371-1 g
Supplier:
Size:
1 g
Product is available in:
£41.00
Estimated delivery Wed 17 Sep
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1143-38-0
Purity:
≥90%
Formulation:
A crystalline solid
Molecular Formula:
C14H10O3
Molecular Weight:
226.2274
Alternative Names:
1,8-dihydroxy-9(10h)-anthracenone, 1,8,9-anthracenetriol, dithranol, nsc 43970, nsc 629313
Product Description:
An anthrone inhibitor of keratinocyte proliferation and a modulator of differentiation; increases apoptosis and inhibits proliferation of NHKs at 2.5 µM; decreases the mitochondrial membrane potential, increases cytochrome c release, and induces perinuclear mitochondrial clustering in NHKs at 5 µM; decreases β-defensin-2 and S100A9 expression and increases IL-6 and IL-8 expression in IL-17A- and IL-22-stimulated NHKs at 0.25 µM; inhibits A23187-stimulated LTB4 production from human neutrophils (IC50 = 7 µM); induces hair regrowth in a DEBR model of alopecia areata
