Demethylzeylasteral
Catalogue number:
CAY28595-1 mg
Supplier:
Size:
1 mg
Product is available in:
£46.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
107316-88-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C29H36O6
Molecular Weight:
480.59254
Alternative Names:
(9β,13α,14β,
Product Description:
A nortriterpenoid; inhibits UGT1A6 and UGT2B7 (Kis = 0.6 and 17.3 µM, respectively); inhibits growth of BAEs and of human U251 glioma cancer cells in vitro (IC50s = 0.21 and ~6.2 µM, respectively); inhibits tumor growth and neovascularization in vivo in a B16/F10 melanoma allograft mouse model at 30 mg/kg per day; decreases renal proteinuria, lesions, immune cell infiltration, and protein levels of TNF-α, COX-2, and ICAM-1 in lupus-prone MRL/lpr mice at 0.12 mg/kg per day; increases kidney transplant survival in recipient rats at 10 mg/kg per day
