MLS-1547
Catalogue number:
CAY27648-10 mg
Supplier:
Size:
10 mg
Product is available in:
£214.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
315698-36-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C19H19ClN4O
Molecular Weight:
354.83322
Alternative Names:
5-chloro-7-[[4-
Product Description:
A G protein-biased agonist of dopamine D2 receptors (EC50 = 0.37 µM in a calcium mobilization assay); inhibits forskolin-induced cAMP accumulation in CHO cells expressing human D2 receptors (EC50 = 0.26 µM) but is inactive in β-arrestin recruitment assays; antagonizes dopamine-induced β-arrestin recruitment in cell-based assays (IC50s = 3.8-9.9 µM); inhibitor of type II secretion in Gram-negative bacteria; inhibits secretion of phospholipase C (PlcH/N) and the virulence factor elastase (LasB) from P. aeruginosa (IC50s = 15 and 13 µM, respectively) and inhibits B. pseudomallei protease secretion by 90.8% at 25 µM
