NSC 228155
Catalogue number:
CAY28856-10 mg
Supplier:
Size:
10 mg
Product is available in:
£170.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
113104-25-9
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C11H6N4O4S
Molecular Weight:
290.2559
Alternative Names:
4-nitro-7-
Product Description:
An activator of EGFR and an inhibitor of the interaction between the KID of CREB and the KIX domain of CBP (IC50 = 0.36 µM); increases phosphorylation of EGFR at Tyr1068 in MDA-MB-468 cells (EC50 = 52 µM), as well as phosphorylation of ERK1 and ERK2; induces transactivation of InsR, EphA1, ErbB2, ErbB3, IGF-1R, Mer, and ROR1 in MDA-MB-468 cells at 100 µM; inhibits CREB- and VP16-CREB-mediated transcription in HEK293T cell-based reporter assays (IC50s = 2.09 and 6.14 µM, respectively); inhibits P. aeruginosa ribonucleotide reductase (IC50 = 26 µM) and is active against P. aeruginosa (MIC = 50 µM)
