Amenamevir
Catalogue number:
CAY27921-25 mg
Supplier:
Size:
25 mg
Product is available in:
£2300.00
Estimated delivery Wed 5 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
841301-32-4
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C24H26N4O5S
Molecular Weight:
482.5532
Alternative Names:
n-(2,6-dimethylphenyl)tetrahydro-n-[2-[[4-(1,2,4-oxadiazol-3-yl)phenyl]amino]-2-oxoethyl]-2h-thiopyran-4-carboxamide, 1,1-dioxide, asp2151
Product Description:
An antiviral inhibitor of HSV-1 helicase-primase complex activity; inhibits recombinant HSV-1 helicase (IC50 = 0.078 µM); inhibits recombinant HSV-1 primase at ≥0.03 µM; inhibits replication of VZV, HSV-1, and HSV-2 in HEF cells (EC50s = 0.047, 0.036, and 0.028 µM, respectively); not cytotoxic to HEF cells (CC50 = >30 µM); inhibits replication of clinal VZV isolates in HEF cells (EC50s = 0.038-0.10 µM); increases survival of cutaneously HSV-1-infected mice in a zosteriform-spread model of progressive HSV-1 infection (ED50 = 1.9 mg/kg twice per day)
