Amenamevir
Catalogue number:
CAY27921-25 mg
Supplier:
Size:
25 mg
Product is available in:
£2300.00
Estimated delivery Mon 16 Mar
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
841301-32-4
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C24H26N4O5S
Molecular Weight:
482.5532
Alternative Names:
n-(2,6-
Product Description:
An antiviral inhibitor of HSV-1 helicase-primase complex activity; inhibits recombinant HSV-1 helicase (IC50 = 0.078 µM); inhibits recombinant HSV-1 primase at ≥0.03 µM; inhibits replication of VZV, HSV-1, and HSV-2 in HEF cells (EC50s = 0.047, 0.036, and 0.028 µM, respectively); not cytotoxic to HEF cells (CC50 = >30 µM); inhibits replication of clinal VZV isolates in HEF cells (EC50s = 0.038-0.10 µM); increases survival of cutaneously HSV-1-infected mice in a zosteriform-spread model of progressive HSV-1 infection (ED50 = 1.9 mg/kg twice per day)
