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Lomerizine (hydrochloride)

Catalogue number:
CAY28374-250 mg
Supplier:
Size:
250 mg
Product is available in:
  • UK
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£95.00 Estimated delivery Tue 12 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

101477-54-7

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C27H30F2N2O3 • 2HCl

Molecular Weight:

541.456866

Alternative Names:

1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-piperazine, dihydrochloride, kb-2796

Product Description:

A voltage-dependent calcium channel blocker; inhibits low- and high-voltage activated calcium currents in rat hippocampal CA1 pyramidal neurons (IC50s = 1.9 and 4 µM, respectively); inhibits vasoconstriction induced by potassium chloride, 5-HT, or vasopressin in isolated rat basilar arteries at 1 µM; reduces neurotoxicity induced by glutamate, NMDA, or kainate in rat retinal primary cell cultures at 1 µM; reduces retinal damage in a rat model of retinal ischemia-reperfusion injury at 1 mg/kg

CAY28374-250 mg: Lomerizine (hydrochlori
CAY28374-250 mg: Lomerizine (hydrochloride)