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HPA-12

Catalogue number:
CAY28350-5 mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
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£333.00 Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

383418-30-2

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C22H37NO3

Molecular Weight:

363.5

Alternative Names:

n-[(1r,3s)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]-dodecanamide, (1r,3s)-hpa-12

Product Description:

A ceramide analog and inhibitor of CERT; inhibits binding of a ceramide probe to the isolated START domain of CERT (EC50 = 4 µM in a TR-FRET assay); inhibits conversion of the fluorescent ceramide analog C5-DMB-Cer to C5-DMB-sphingomyelin in CHO and HeLa cells at 2.5 µM; inhibits sphingomyelin synthesis in wild-type, but not ATP-dependent ceramide transport-deficient, CHO cells at 1 µM

CAY28350-5 mg: HPA-12
CAY28350-5 mg: HPA-12