AUT1
Catalogue number:
CAY28599-50 mg
Supplier:
Size:
50 mg
Product is available in:
£270.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1311136-84-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C18H19N3O4
Molecular Weight:
341.36128
Alternative Names:
5r-ethyl-3-
Product Description:
A positive modulator of Kv3.1b, Kv3.2a, and Kv3.3 (EC50s = 4.7, 4.9, and 31.6 µM, respectively, in a patch-clamp assay); selective for Kv3.1b, Kv3.2a, and Kv3.3 over Kv1.5 and Kv7.1/minK channels but also inhibits the 5-HT transporter, 5-HT3 receptor, and α1 subunit-containing nAChR in a panel of 26 ion channels, receptors, and transporters; increases tetraethylammonium-induced decreases in the firing frequency and amplitude of action potentials in mouse somatosensory cortex slices at 1 and 10 µM
