Tiratricol
Catalogue number:
CAY28729-50 mg
Supplier:
Size:
50 mg
Product is available in:
£46.00
Estimated delivery Fri 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
51-24-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C14H9I3O4
Molecular Weight:
621.93227
Alternative Names:
4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-benzeneacetic acid, 3,3′,5-triiodothyroacetic acid
Product Description:
A thyroid hormone receptor agonist (EC50s = 1.81 and 4.13 nM for TRα and TRβ, respectively, in reporter assays); stimulates cerebellar Purkinje cell dendritogenesis and cortical myelination in Mct8/Oatp1c1 double knockout mice at 50 or 400 ng/g; reduces methimazole-induced goiter in rats at 25 µg per animal; decreases TLR2 levels and the phosphorylation of Akt and MAPK in HEK-Blue™ cells expressing human TLR2; reduces liver tissue necrosis in a mouse model of concanavalin A-induced hepatitis
