Tiratricol
Catalogue number:
CAY28729-50 mg
Supplier:
Size:
50 mg
Product is available in:
£46.00
Estimated delivery Mon 30 Mar
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
51-24-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C14H9I3O4
Molecular Weight:
621.93227
Alternative Names:
4-(4-hydroxy-
Product Description:
A thyroid hormone receptor agonist (EC50s = 1.81 and 4.13 nM for TRα and TRβ, respectively, in reporter assays); stimulates cerebellar Purkinje cell dendritogenesis and cortical myelination in Mct8/Oatp1c1 double knockout mice at 50 or 400 ng/g; reduces methimazole-induced goiter in rats at 25 µg per animal; decreases TLR2 levels and the phosphorylation of Akt and MAPK in HEK-Blue™ cells expressing human TLR2; reduces liver tissue necrosis in a mouse model of concanavalin A-induced hepatitis
