Lomerizine (hydrochloride)
Catalogue number:
CAY28374-500 mg
Supplier:
Size:
500 mg
Product is available in:
£148.00
Estimated delivery Tue 9 Jun
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
101477-54-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C27H30F2N2O3 • 2HCl
Molecular Weight:
541.456866
Alternative Names:
1-[bis(4-fluoro
Product Description:
A voltage-dependent calcium channel blocker; inhibits low- and high-voltage activated calcium currents in rat hippocampal CA1 pyramidal neurons (IC50s = 1.9 and 4 µM, respectively); inhibits vasoconstriction induced by potassium chloride, 5-HT, or vasopressin in isolated rat basilar arteries at 1 µM; reduces neurotoxicity induced by glutamate, NMDA, or kainate in rat retinal primary cell cultures at 1 µM; reduces retinal damage in a rat model of retinal ischemia-reperfusion injury at 1 mg/kg
