12(R)-HETE
Catalogue number:
CAY34560-100 ug
Supplier:
Size:
100 µg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
82337-46-0
Purity:
≥98%
Formulation:
A 100 µg/ml solution in ethanol
Molecular Formula:
C20H32O3
Molecular Weight:
320.5
Alternative Names:
12r-hydroxy-
Product Description:
An active metabolite of arachidonic acid; binds to the TP receptor in washed isolated human platelets (IC50 = 0.734 µM); inhibits I-BOP-induced platelet aggregation (IC50 = 3.6 µM); selectively binds to BLT2 over BLT1 at 5 µM in CHO cell membranes expressing the human receptors; increases the proliferation of HT-29 cells at 1 µM; inhibits bovine corneal Na+/K+-ATPase; decreases intraocular pressure in rabbits at 1, 10, or 50 µg/eye; intracerebroventricular administration decreases LPS-induced pyresis in rats at 10 µg/animal
