(±)5-HETE lactone
Catalogue number:
CAY34215-50 ug
Supplier:
Size:
50 µg
Product is available in:
£154.00
Estimated delivery Wed 8 Oct
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
81517-87-5
Purity:
≥98%
Formulation:
A solution in acetonitrile
Molecular Formula:
C20H30O2
Molecular Weight:
302.5
Alternative Names:
tetrahydro-6-(1e,3z,6z,9z)-1,3,6,9-pentadecatetraen-1-yl-2h-pyran-2-one, (±)5-hydroxyeicosatetraenoic acid lactone
Product Description:
(±)5-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of (±)5-HETE. (±)5-HETE lactone is an inhibitor of 5-LO from rat basophilic leukemia cells with an IC50 of 27 µM. The lactone is several times more potent than the linear (±)5-HETE.{690}