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(−)-Nutlin-3

Catalogue number:
CAY18585-25 mg
Supplier:
Size:
25 mg
Product is available in:
  • UK
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£1269.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

675576-98-4

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C30H30Cl2N4O4

Molecular Weight:

581.5

Alternative Names:

4-[[(4s,5r)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1h-imidazol-1-yl]carbonyl]-2-piperazinone, nutlin 3a

Product Description:

An inhibitor of the p53-Mdm2 interaction (IC50 = 0.09 µM); increases p53 levels, induces apoptosis, and reduces cell viability in HCT116, SJSA-1, and RKO cells; reduces tumor volume in SJSA-1, MHM, LNCaP, and 22Rv1 mouse xenograft models at 200 mg/kg

CAY18585-25 mg: (-)-Nutlin-3
CAY18585-25 mg: (-)-Nutlin-3