13,14-dihydro Prostaglandin E1
Catalogue number:
CAY13610-5 mg
Supplier:
Size:
5 mg
Product is available in:
£501.00
Estimated delivery Wed 22 Jul
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
19313-28-1
Purity:
≥98%
Formulation:
A solution in methyl acetate
Molecular Formula:
C20H36O5
Molecular Weight:
356.5
Alternative Names:
9-oxo-11α,15s-
- MSDS: View or download
Product Description:
13,14-dihydro PGE1 is a biologically active metabolite of PGE1 with comparable potency to the parent compound.{4168,182} It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively.{1607} 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 of 40 nM.{960} Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hybrid cells with a Kact of 668 nM.{1926}
