2',3',5'-Triacetyluridine
Catalogue number:
CAY27445-25 g
Supplier:
Size:
25 g
Product is available in:
£176.00
Estimated delivery Wed 8 Oct
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
4105-38-8
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C15H18N2O9
Molecular Weight:
370.3115
Alternative Names:
2',3',5'-triacetate uridine, 2',3',5'-tri-o-acetyluridine, pn401, rg2133, uridine triacetate
Product Description:
A prodrug of uridine; decreases neurodegeneration in the piriform cortex and striatum, as well as reduces the amount of huntingtin-positive aggregates and increases BDNF protein levels in the piriform cortex in a transgenic mouse model of Huntington’s disease at 6% in the diet; improves rotarod performance and increases survival in transgenic mouse models of Huntington’s disease; reverses toxicity and increases survival in a mouse model of DPD deficiency-induced 5-FU overdose at 2,000 mg/kg three times per day beginning within 24 hours of 5-FU administration
