Geniposide

An iridoid glycoside with diverse biological activities; reduces exudate volume and nitrite levels in a rat model of carrageenan-induced air pouch inflammation at 0.1 mg/pouch; prevents prevents carrageenan-induced paw edema in rats at 100 mg/kg, p.o.; reduces serum levels of ALT and AST and hepatic levels of MDA as well as decreases in hepatic levels of SOD and GPX in a rat model of high-fat diet-induced NASH at 50 and 100 mg/kg; prevents increases in apoptosis and decreases in the number of dopaminergic neurons in the substantia nigra in a mouse model of MPTP-induced Parkinson's disease at 100 mg/kg; improves motor coordination in the rotarod and swim tests in a rat model of Parkinson's disease