Fraxetin
Catalogue number:
CAY28011-50 mg
Supplier:
Size:
50 mg
Product is available in:
£333.00
Estimated delivery Wed 24 Jun
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
574-84-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C10H8O5
Molecular Weight:
208.2
Alternative Names:
7,8-dihydroxy-
Product Description:
A coumarin with diverse biological activities; scavenges DPPH radicals, ABTS radicals, and hydrogen peroxide in cell-free assays (IC50s = 44.1, 37.4, and 40.5 µM, respectively); selectively reduces cell viability in a panel of six NSCLC cell lines (IC50s = 20.12-61.36 µM) over noncancerous cell lines (IC50s = >100 µM); reduces levels of AST, ALT, and TBIL in serum, decreases hepatic expression of TNF-α, IL-6, IL-1β, and COX-2, and attenuates hepatic fibrosis in a rat model of carbon tetrachloride-induced liver fibrosis at 25 and 50 mg/kg
