Aminooxyacetic Acid (hydrochloride)
Catalogue number:
CAY28298-250 mg
Supplier:
Size:
250 mg
Product is available in:
£52.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2921-14-4
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
C2H5NO3 • 1/2HCl
Molecular Weight:
109.3
Alternative Names:
2-(aminooxy)-
Product Description:
A GABA-T inhibitor (Ki = 9.16 µM) that induces GABA accumulation in the brain; inhibits CBS and CSE (IC50s = 8.5 and 1.1 µM, respectively); decreases GABA-T activity and increases GABA levels in all regions of rat brain at 100 mg/kg; decreases GABA-T activity and increases GABA in mouse brain at 13 mg/kg; inhibits 3-mercaptopropionic acid-, strychnine-, and pentetrazole-induced seizures in mice (ED50s = 53, 130, and 85 mg/kg, respectively); exhibits neurotoxicity in the chimney test (ED50 = 62 mg/kg) and is lethal (LD50 = 105 mg/kg) to mice
