Setipiprant
Catalogue number:
CAY28291-5 mg
Supplier:
Size:
5 mg
Product is available in:
£69.00
Estimated delivery Fri 5 Jun
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
866460-33-5
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C24H19FN2O3
Molecular Weight:
402.417743
Alternative Names:
8-fluoro-1,2,
Product Description:
An orally bioavailable antagonist of CRTH2/DP2 (IC50 = 6 nM for the human receptor); selective for CRTH2/DP2 over DP1 in a radioligand binding assay (IC50 = 1,290 nM) and EP2 and EP4 in a β-arrestin assay (IC50s = 2,600 and >10,000 nM, respectively); inhibits PGD2-induced calcium flux in HEK293 cells expressing human CRTH2/DP2 (IC50 = 30 nM); inhibits PGD2-induced shape change in human eosinophils (IC50 = 235 nM)
