(−)-Bicuculline methochloride
Catalogue number:
CAY27802-10 mg
Supplier:
Size:
10 mg
Product is available in:
£146.00
Estimated delivery Tue 16 Dec
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
53552-05-9
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C21H20NO6 • Cl
Molecular Weight:
417.83934
Alternative Names:
(5r)-5-[(6s)-
Product Description:
An enantiomer of (+)-bicuculline methochloride; increases the firing rate in rat cortical neurons similar to the (+) isomer, but lacks GABA antagonist activity; inhibits sodium-independent GABA receptor binding (IC50 = 500 µM), which is approximately 100-fold less potent than the (+) isomer, but there is no stereoselectivity for sodium-dependent GABA receptor binding
