£62.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
299953-00-7
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
C10H8N2O2S
Molecular Weight:
220.3
Alternative Names:
2-amino-5-[(4-
- MSDS: View or download
Product Description:
A MRN complex inhibitor; inhibits DSB-induced H2AX phosphorylation (IC50 = 66 µM in X. laevis cell-free extracts); inhibits the exonuclease activity of Mre11 in a cell-free assay at 100 µM; induces cell cycle arrest at the G2 phase in TOSA4 cells and inhibits homology-dependent repair in HEK293 cells in a concentration-dependent manner; reduces tumor growth in an LA-N-5 mouse xenograft model when encapsulated in nanoparticles at 50 mg/kg
