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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
667463-62-9
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
356.2
Alternative Names:
6-bromo-3-[(3e)-1,3-dihydro-3-(hydroxyimino)-2h-indol-2-ylidene]-1,3-dihydro-(3z)-2h-indol-2-one, gsk3 inhibitor ix, 6-bromoindirubin-3'-oxime, mls 2052
- Data sheet: View or download
- MSDS: View or download
Product Description:
A cell-permeable bis-indolo (indirubin) compound that acts as a highly potent, selective, reversible, and ATP-competitive inhibitor of GSK3α/β (IC50 = 5 nM); inhibition of GSK activates the Wnt-signaling pathway and sustains pluripotency in human and mouse ESCs; maintains self-renewal in human and mouse embryonic stem cells as well as induces the differentiation of neonatal cardiomyocytes
Storage Temperature:
-20°C