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PD 0325901

Catalogue number:
CAY13034-5 mg
Supplier:
Size:
5 mg
Product is available in:
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£69.00 Estimated delivery Wed 22 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

391210-10-9

Purity:

≥90%

Formulation:

A crystalline solid

Molecular Formula:

C16H14F3IN2O4

Molecular Weight:

482.2

Alternative Names:

n-[(2r)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide

Product Description:

A potent MEK inhibitor that suppresses phosphorylation of ERK in murine colon 26 tumors with an IC50 value of 0.33 nM; suppression of ERK activation with 1 µM PD 0325901 combined with 3 µM CHIR99021 (a glycogen synthase kinase-3 inhibitor) prevents cell differentiation and sustains self renewal of mouse embryonic stem cells for at least eight passages

CAY13034-5 mg: PD 0325901
CAY13034-5 mg: PD 0325901