www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

15(R)-15-methyl Prostaglandin D2

Catalogue number:
CAY12720-1 mg
Supplier:
Size:
1 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£172.00 Estimated delivery Tue 25 Jun
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

210978-26-0

Purity:

≥95%

Formulation:

A solution in methyl acetate

Molecular Weight:

366.5

Alternative Names:

9α,15r-dihydroxy-11-oxo-15-methyl-prosta-5z,13e-dien-1-oic acid, 15(r)-15-methyl pgd2

Product Description:

The physiological actions of PGD2 include regulation of sleep, lowering of body temperature, inhibition of platelet aggregation and relaxation of vascular smooth muscle.{328,1185,580} PGD2 mediates its effects by 2 distinct G-protein-coupled receptors, DP1{3128} and CRTH2/DP2.{10722,9769} 15(R)-15-methyl PGD2 is a potent, selective agonist for the CRTH2/DP2 receptor.{10723} The EC50 values for eosinophil CD11b expression, actin polymerization, and chemotaxis are 1.4, 3.8, and 1.7 nM, respectively, each of which is approximately 3-5 fold lower than those for PGD2. In contrast the EC50 for the DP1-mediated increase in platelet cAMP by 15(R)-15-methyl PGD2 is >10 µM.{10723}

Storage Temperature:

-20°C

CAY12720-1 mg: 15(R)-15-methyl Prostagla
CAY12720-1 mg: 15(R)-15-methyl Prostaglandin D2
Details Cat number & supplier Size Price
15-deoxy-Δ12,14-Prostaglandin D2 CAY12700-500 ug · Cayman Chemical
CAY12700-500 ug
Cayman Chemical
500 µg £130.00
500 µg
view
15-deoxy-Δ12,14-Prostaglandin D2 CAY12700-5 mg · Cayman Chemical
CAY12700-5 mg
Cayman Chemical
5 mg £1038.00
5 mg
view
15(R)-15-methyl Prostaglandin D2 CAY12720-500 ug · Cayman Chemical
CAY12720-500 ug
Cayman Chemical
500 µg £102.00
500 µg
view
15-deoxy-Δ12,14-Prostaglandin D2 CAY12700-1 mg · Cayman Chemical
CAY12700-1 mg
Cayman Chemical
1 mg £247.00
1 mg
view
15(S)-15-methyl Prostaglandin D2 CAY12730-1 mg · Cayman Chemical
CAY12730-1 mg
Cayman Chemical
1 mg £179.00
1 mg
view
Δ12-Prostaglandin D2 CAY12650-500 ug · Cayman Chemical
CAY12650-500 ug
Cayman Chemical
500 µg £67.00
500 µg
view
Δ12-Prostaglandin D2 CAY12650-5 mg · Cayman Chemical
CAY12650-5 mg
Cayman Chemical
5 mg £563.00
5 mg
view
Δ12-Prostaglandin D2 CAY12650-10 mg · Cayman Chemical
CAY12650-10 mg
Cayman Chemical
10 mg £992.00
10 mg
view
Δ12-Prostaglandin D2 CAY12650-1 mg · Cayman Chemical
CAY12650-1 mg
Cayman Chemical
1 mg £120.00
1 mg
view
16,16-dimethyl Prostaglandin D2 CAY12750-1 mg · Cayman Chemical
CAY12750-1 mg
Cayman Chemical
1 mg £125.00
1 mg
view