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ELISA, Immunohistochemistry, IF Microscopy, Western Blot
Rabbit
H. sapiens (Human); Mus musculus (Mouse); Rat
IgG
Polyclonal
Anti-ADORA2B antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the C-terminus of huma
Adenosine receptor A2b, ADORA2
The adenosine receptor ADORA2B is a member of the G protein-coupled receptor superfamily and is an integral membrane protein that stimulates adenylate cyclase activity in the presence of adenosine (1,2) . Extracellular adenosine triggers a potent anti-inflammatory response that is mediated in part by ADORA2B including the stimulation of IL-10 production (3-5) . Activation of ADORA2B can also enhance the abundance of regulatory T cells (Tregs) , a class of cells that work to constrain inflammation (6) . Anti-ADORA2B Antibody has been tested for use in ELISA, immunohistochemistry, immunofluorescence, and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 41 kDa in Western Blots of specific cell lysates and tissues.
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended sto
