www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

(Z)-Ligustilide

Catalogue number:
CAY26908-25 mg
Supplier:
Size:
25 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£214.00 Estimated delivery Wed 13 May
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

81944-09-4

Purity:

≥95%

Formulation:

A neat oil

Molecular Formula:

C12H14O2

Molecular Weight:

190.23836

Alternative Names:

3z-butylidene-4,5-dihydro-1(3h)-isobenzofuranone, cis-ligustilide, ligustilide a

Product Description:

A phthalide with diverse biological activities; inhibits autophagy and restores Nurr77 expression and tamoxifen sensitivity in tamoxifen-resistant MCF-7 cells; increases cerebral expression of Nrf2 and HO-1 and reduces infarct volume and neuronal loss in a rat model of cerebral ischemia and reperfusion injury from 8-32 mg/kg; decreases mechanical and thermal hyperalgesia in a rat model of CFA-induced inflammatory pain; restores gait coordination, reduces spinal cord iNOS mRNA expression, and inhibits production of PGE2, TNF-α, and IL-1β in a rat model of spinal cord injury

CAY26908-25 mg: (Z)-Ligustilide
CAY26908-25 mg: (Z)-Ligustilide