Heclin
Catalogue number:
CAY26139-1 mg
Supplier:
Size:
1 mg
Product is available in:
£46.00
Estimated delivery Tue 12 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
890605-54-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C17H17NO3
Molecular Weight:
283.32182
Alternative Names:
n-(4-acetyl
Product Description:
An inhibitor of HECT E3 ubiquitin ligases (IC50s = 6.8, 6.3, and 6.9 µM for Smurf2, Nedd4, and WWP1 HECT ligase domains, respectively); inhibits autoubiquitination of Smurf2 in HEK293 cells expressing the human enzyme (IC50 = 9 µM); reduces ubiquitination of Dishevelled 2 in HEK293 cells expressing Smurf2, Nedd4, or WWP2; cytotoxic to HEK293 cells (IC50 = 45 µM)
