H-89 (hydrochloride)
Catalogue number:
CAY10010556-50 mg
Supplier:
Size:
50 mg
Product is available in:
£451.00
Estimated delivery Thu 25 Sep
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
130964-39-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C20H20BrN3O2S • 2HCl
Molecular Weight:
519.3
Alternative Names:
n-[2-[[3-(4-bromophenyl)-2-propen-1-yl]amino]ethyl]5-isoquinolinesulfonamide, dihydrochloride, 5-isoquinolinesulfonamide, protein kinase inhibitor h-89
Product Description:
A potent, non-selective inhibitor of PKA with an IC50 value of 0.14 µM (Ki = 48 nM) that is widely used to disrupt PKA signaling; inhibits S6K1, MSK1, ROCK2, PKBa, and MAPKAP-K1b with IC50 values of 0.08, 0.12, 0.27, 2.6, and 2.8 µM, respectively
