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Simvastatin

Catalogue number:
CAY10010344-50 mg
Supplier:
Size:
50 mg
Product is available in:
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£105.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

79902-63-9

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C25H38O5

Molecular Weight:

418.6

Alternative Names:

2,2-dimethyl-1s,2,3r,7s,8s,8ar-hexahydro-3,7-dimethyl-8-[2-[(2r,4r)-tetrahydro-4-hydroxy-6-oxo-2h-pyran-2-yl]ethyl]-1-naphthalenyl ester, but

Product Description:

An HMG-CoA reductase inhibitor (Ki = 0.12 nM); reduces plasma cholesterol levels in rats and dogs at 1.2 and 8 mg/kg, respectively; suppresses TNF-induced NF-κB activation (IC50 = ~13 µM) and potentiates apoptosis in human myeloid leukemia cells; inhibits GPX4, increases MDA levels, and induces ferroptosis in MDA-MB-231 and MCF-7 breast cancer cells

CAY10010344-50 mg: Simvastatin
CAY10010344-50 mg: Simvastatin