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DRB

Catalogue number:
CAY10010302-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
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  • Europe
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  • Rest of World
£45.00 Estimated delivery Wed 4 Mar
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

53-85-0

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C12H12Cl2N2O4

Molecular Weight:

319.1

Alternative Names:

5,6-dichloro-1-β-d-ribofuranosyl-1h-benzimidazole, benzimidazole, nsc 401575

Product Description:

Inhibits CKII (IC50 range of 4-10 µM), Cdk7 (IC50 = ~20 µM), Cdk8 (IC50 = ~20 µM), and Cdk9 (IC50 = 3 µM); inhibits elongation during RNA polymerase II transcription; triggers p53-dependent apoptosis of human colon adenocarcinoma cells; inhibits trans-activated transcription of the Tat protein of HIV-1 (IC50 = ~4 µM)

CAY10010302-10 mg: DRB
CAY10010302-10 mg: DRB