6-Aminonicotinamide
Catalogue number:
CAY10009315-250 mg
Supplier:
Size:
250 mg
Product is available in:
£45.00
Estimated delivery Fri 2 Jan
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
329-89-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C6H7N3O
Molecular Weight:
137.1
Alternative Names:
6-amino-3-
Product Description:
A well-established inhibitor of the NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase (Ki = 0.46 µM) which interferes with glycolysis; through ATP depletion, synergizes with chemotherapy drugs, like cisplatin, in killing cancer cells (IC50 = 0.5 mM); reduces cardiovascular oxidative injury following ischemia/reperfusion; causes glial neurodegeneration
