LNS 8801
Catalogue number:
CAY10008933-1 mg
Supplier:
Size:
1 mg
Product is available in:
£50.00
Estimated delivery Wed 22 Jul
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
881639-98-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C21H18BrNO3
Molecular Weight:
412.3
Alternative Names:
rel-
Product Description:
LNS 8801 is a nonsteroidal, high-affinity, selective agonist of GPR30 that binds with a Ki value of 11 nM. Competitive binding studies in estrogen receptor α- (ERα-) and ERβ-expressing cells yielded Ki values for estradiol of 0.30 and 0.38 nM, respectively, with no substantial binding of LNS 8801 at 1 µM.{14210} The discovery of LNS 8801, a compound that does not bind classical ERs, should facilitate further physiological experiments to define the role of GPR30 in vivo.
