Zafirlukast
Catalogue number:
CAY10008282-10 mg
Supplier:
Size:
10 mg
Product is available in:
£36.00
Estimated delivery Mon 4 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
107753-78-6
Purity:
≥97%
Formulation:
A crystalline solid
Molecular Formula:
C31H33N3O6S
Molecular Weight:
575.7
Alternative Names:
[3-
Product Description:
A CysLT1 receptor antagonist (IC50 = 0.014 µM in a cell-based calcium mobilization assay); selective for CysLT1 over CysLT2 receptors (IC50 = 58 µM); inhibits LTD4-induced mucus secretion in isolated guinea pig trachea (IC50 = 0.6 µM); inhibits ovalbumin-induced increases in tracheal mucus secretion in ovalbumin-sensitized guinea pigs by 65% at 5 µM; inhibits LTD4-induced bronchoconstriction in anesthetized guinea pigs (ED50 = 61 nmol/kg, i.v.)
