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Erastin2

Catalogue number:
CAY27087-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
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£552.00 Estimated delivery Fri 15 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1695533-44-8

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C36H35ClN4O4

Molecular Weight:

623.14036

Alternative Names:

2-[[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]methyl]-3-[4-(1-methylethoxy)[1,1'-biphenyl]-3-yl]-4(3h)-quinazolinone, 35mew28

Product Description:

A ferroptosis inducer and inhibitor of the system xc- cystine/glutamate transporter; inhibits glutamate release in CCF-STTG1 cells (IC50 = 0.0035 µM); induces cell death in HAP1 cells at 5 µM, an effect that can be blocked by ferrostatin-1 or deferoxamine; induces ferroptotic cell death in HT-1080 cells (EC50 = 0.15 µM); increases lipid peroxidation in HT-1080 cells at 1 µM

CAY27087-10 mg: Erastin2
CAY27087-10 mg: Erastin2