CMPD101
Catalogue number:
CAY26808-10 mg
Supplier:
Size:
10 mg
Product is available in:
£246.00
Estimated delivery Mon 8 Jun
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
865608-11-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C24H21F3N6O
Molecular Weight:
466.458589
Alternative Names:
3-[[[4-methyl-
Product Description:
A GRK2 and GRK3 inhibitor (IC50s = 18 and 5.4 nM, respectively); selective for GRK2 and GRK3 over GRK1, GRK5, GRK6, and GRK7 (IC50s = 3,100, 2,300, >30,000, and 25,000 nM, respectively), as well as ROCK2 and PKCα (IC50s = 1,400 and 8,100 nM, respectively); induces cAMP accumulation in HEK293 cells expressing human β2-adrenergic receptors (EC50 = 10 µM); inhibits electrical field stimulation-, norepinephrine-, phenylephrine-, endothelin-1-, and U-46619-induced contractions in isolated human prostate strips at 50 µM
