CMPD101
Catalogue number:
CAY26808-10 mg
Supplier:
Size:
10 mg
Product is available in:
£246.00
Estimated delivery Tue 14 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
865608-11-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C24H21F3N6O
Molecular Weight:
466.458589
Alternative Names:
3-[[[4-methyl-
Product Description:
A GRK2 and GRK3 inhibitor (IC50s = 18 and 5.4 nM, respectively); selective for GRK2 and GRK3 over GRK1, GRK5, GRK6, and GRK7 (IC50s = 3,100, 2,300, >30,000, and 25,000 nM, respectively), as well as ROCK2 and PKCα (IC50s = 1,400 and 8,100 nM, respectively); induces cAMP accumulation in HEK293 cells expressing human β2-adrenergic receptors (EC50 = 10 µM); inhibits electrical field stimulation-, norepinephrine-, phenylephrine-, endothelin-1-, and U-46619-induced contractions in isolated human prostate strips at 50 µM
