CAY10441
Catalogue number:
CAY10005186-5 mg
Supplier:
Size:
5 mg
Product is available in:
£209.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
221529-58-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C19H23N3O
Molecular Weight:
309.4
Alternative Names:
4,5-
Product Description:
An IP receptor antagonist; selective for the IP receptor over EP1, EP2, EP3, EP4, FP, and TP receptors and a panel of 30 other receptors and ion channels but does bind α2A-adrenergic and imidazoline I2 receptors; inhibits carbaprostacyclin-induced cAMP accumulation in SH-SY5Y cells (pKB = 8.8) and cicaprost-induced vasorelaxation of isolated human pulmonary arteries (pA2 = 8.2); decreases cicaprost-induced inhibition of platelet aggregation in human platelet-rich plasma; reduces acetic acid-induced writhing and carrageenan-induced paw hyperalgesia in rats (ED50s = 4 and 2.8 mg/kg, respectively)
