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Estimated delivery Wed 8 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
486-66-8
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
254.2
Alternative Names:
7-hydroxy-3-(4-hydroxyphenyl)-4h-1-benzopyran-4-one
- Data sheet: View or download
- MSDS: View or download
Product Description:
An isoflavone; binds to ERβ (Ki = 2.8 µM) but not ERα up to 1 mM; estrogenic in vitro, increasing ERE-mediated gene transcription via ERβ (EC50 = 2.8 µM); an inhibitor of CAVII and CAXII (Kis = 4.2 and 56 nM, respectively) and selective for them over CAI, II, and IV (Kis = >10,000, >10,000, and 718.7 nM, respectively); reduces tumor growth in a PC3 prostate cancer mouse orthtopic model at 50 mg/kg per day
Storage Temperature:
-20°C
