www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

3',4'-Dihydroxyflavone

Catalogue number:
CAY35226-500 mg
Supplier:
Size:
500 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£385.00 Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

4143-64-0

Purity:

≥95%

Formulation:

A crystalline solid

Molecular Formula:

C15H10O4

Molecular Weight:

254.2375

Alternative Names:

2-(3,4-dihydroxyphenyl)-4h-1-benzopyran-4-one, 3',4'-dhf

Product Description:

A synthetic flavonoid with diverse biological activities; inhibits TNKS1 and TNKS2 (IC50s = 0.23 and 0.17 µM for the human enzymes, respectively); active against L. donovani, T. brucei, and T. cruzi (IC50s = 2, 1.1, and 10.1 µg/ml, respectively); induces apoptosis in and inhibits migration of GL15 cells at 50 µM; prevents LPS-induced increases in brain levels of COX-2 and iNOS in a mouse model of neuroinflammation at 5 mg/kg