Leptomycin B
Catalogue number:
CAY10004976-5 ug
Supplier:
Size:
5 µg
Product is available in:
£55.00
Estimated delivery Mon 8 Jun
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
87081-35-4
Purity:
≥98%
Formulation:
A 25 µg/ml solution in ethanol
Molecular Formula:
C33H48O6
Molecular Weight:
540.7
Alternative Names:
19-
Product Description:
A potent inhibitor of nuclear transport; blocks the interaction of CRM1 with NES, preventing the export of a broad range of proteins; inhibits export of mRNA from the nucleus by blocking the nuclear export of mRNA-binding proteins; blocks the nuclear export of p53 and prevents entry of human normal fibroblasts into the S phase of the cell cycle, thus inhibiting proliferation; originally identified as an antifungal agent
