Sorafenib N-oxide
Catalogue number:
CAY27830-5 mg
Supplier:
Size:
5 mg
Product is available in:
£547.00
Estimated delivery Mon 11 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
583840-03-3
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C21H16ClF3N4O4
Molecular Weight:
480.824209
Alternative Names:
4-[4-[[[[4-
Product Description:
An active metabolite of sorafenib; inhibits FLT3-ITD (Kd = 70 nM); inhibits proliferation of MV4-11 AML cells expressing FLT3-ITD (IC50 = 25.8 nM); selective for AML cell lines containing FLT3-ITD over lines containing wild-type FLT3 (IC50s = 3.9-13.3 µM); a linear-mixed inhibitor of CYP3A4 (Ki = 15 µM)
