EP3 Receptor Polyclonal Antibody

Immunogen: Synthetic peptide from an internal region of human EP3 receptor • Host: Rabbit • Cross Reactivity: (+) EP3 Receptor; (-) EP1, EP2, and EP4 Receptors • Species Reactivity: (+) Human, bovine, mouse, and rat; other species not tested. • Applications: ICC, IHC, and WB • As a result of splice variation, the EP3 receptor can be expressed as multiple isoforms that differ in the length and sequence of their C-terminal tails. The signal transduction mechanism varies depending on the isoform being expressed, implicating the importance of the C-terminal region of the receptor for coupling to G-proteins.