www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

CaMKII (Phospho-Thr286/Thr287) Monoclonal Antibody (Clone 22B1)

Catalogue number:
CAY10011438-100 ug
Supplier:
Size:
100 µg
£660.00
Shipping is calculated in checkout
This product is no longer available to order.
Applications:

ELISA, IF, IHC, IP, WB

Antibody Host:

Mouse

Antibody Isotype:

IgG1

Immunogen:

synthetic peptide

Alternative Names:

calcium/calmodulin-dependent protein kinase ii

Product Description:

Antigen: mouse recombinant CaMKII • Host: mouse, clone 22B1 • Isotype: IgG1 • Cross Reactivity: (+) rat CaMKII • Application(s): ELISA, IF, IP, and WB • CaMKII functions in neural synaptic stimulation and T-cell receptor signaling. The binding of Ca2+/calmodulin to its regulatory domain releases its auto inhibitory effect and activates the kinase. This kinase activation results in autophosphorylation at Thr286. PP1 dephosphorylates phospho-CaMKII at Thr286 and PKA prevents this dephosphorylation.