AX-024 (hydrochloride)
Catalogue number:
CAY27333-10 mg
Supplier:
Size:
10 mg
Product is available in:
£436.00
Estimated delivery Fri 24 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1704801-24-0
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C21H22FNO2 • HCl
Molecular Weight:
375.863963
Alternative Names:
1-[[4-(4-
Product Description:
CD3ε-Nck interaction; inhibits T cell receptor-triggered T cell activation (IC50 = 1 nM); prevents CD4+ T cell and macrophage infiltration to the cerebellum and spinal cord and improves neurological impairments in a MOG35-55 mouse model of EAE at 10 mg/kg per day; prevents the infiltration of eosinophils, macrophages, and neutrophils into the airway in an ovalbumin-sensitized mouse model of allergic airway disease at 50 mg/kg
