Applications:
WB
Antibody Host:
Rabbit
Immunogen:
phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser33,37 of human .beta.-catenin
Alternative Names:
anti-phospho-ser33,37 β-catenin
- Data sheet: View or download
- MSDS: View or download
Product Description:
Antigen: phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser33,37 of human β-catenin · Host: rabbit · Cross-reactivity: (+) human β-catenin · Application: WB • β-Catenin is a central component of the cadherin cell adhesion complex and plays an essential role in neural development in the Wingless/Wnt signaling pathway. It is thought to be regulated by the sequential phosphorylation of Ser29, Ser33, Ser37, and Thr41 by GSK3β. This hyperphosphorylation promotes the ubiquitylation and targeted destruction of β-catenin.
Storage Temperature:
-20°C