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Gramicidin A

Catalogue number:
CAY26384-5 mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
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£140.00 Estimated delivery Tue 14 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

11029-61-1

Purity:

≥90%

Formulation:

A solid

Molecular Formula:

C99H140N20O17

Molecular Weight:

1882.2955

Alternative Names:

(r)-2-((2s,5r,8s,11r,14s,17r,20s,26s)-2-((1h-indol-3-yl)methyl)-17-isobutyl-5,8,11,26-tetraisopropyl-14,20-dimethyl-4,7,10,13,16,19,22,27,28-nonaoxo-3,6,9,12,15,18,2

Product Description:

A channel-forming ionophore; a peptide component of the antibiotic gramicidin; forms channels in model membranes that are permeable to monovalent cations, protons, and water; induces degradation of HIF-1α in HEK293 cells and reduces growth in a human renal cell carcinoma mouse xenograft model at 0.22 mg/kg three times per week; reduces viral yield in WI-38 fibroblasts inoculated with isolates of HSV-1 and HSV-2 (IC50 = 0.3 µg/ml for all); commonly been used to study channel structure and function

CAY26384-5 mg: Gramicidin A
CAY26384-5 mg: Gramicidin A