GSK180736A
Catalogue number:
CAY26182-5 mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
817194-38-0
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C19H16FN5O2
Molecular Weight:
365.361243
Alternative Names:
4-(4-fluoro
Product Description:
A ROCK1 and GRK2 inhibitor (IC50s = 14 and 0.77 µM, respectively); selective for GRK2 over GRK1, GRK5, and PKA (IC50 = >100 µM for all); selective for ROCK1 over RSK1 and p20S6K (IC50s = 3,100 and 2,850 nM, respectively); increases maximum contractility in isolated mouse cardiomyocytes at 1 µM
