GAT229
Catalogue number:
CAY24486-1 mg
Supplier:
Size:
1 mg
Product is available in:
£154.00
Estimated delivery Wed 21 Jan
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
889860-85-9
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C22H18N2O2
Molecular Weight:
342.3906
Alternative Names:
3-[(1s)-2-
- MSDS: View or download
Product Description:
An allosteric modulator of the CB1 receptor; the S-(–) enantiomer of GAT211; enhances the binding of CP 55,940 to CHO cells expressing hCB1 by 130% at 1 µM; enhances the activity of 2-AG, AEA, and CP 55,940 in arrestin2, as well as ERK1/2 and PLCβ3 phosphorylation, assays to HEK293 cells expressing hCB1; enhances depolarization-induced suppression of excitation but does not inhibit excitatory postsynaptic currents in murine autaptic hippocampal neurons at 1 µM; reduces intraocular pressure by 5.8 and 7.7 mm Hg after 6 and 12 hours, respectively, in a nee transgenic mouse model of ocular hypertension at 0.2%, topical
