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ARN14988

Catalogue number:
CAY24284-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
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  • Europe
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  • Rest of World
£476.00 Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1502027-70-4

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C16H24ClN3O5

Molecular Weight:

373.8

Alternative Names:

5-chloro-3-[(hexylamino)carbonyl]-3,6-dihydro-2,6-dioxo-1(2h)-pyrimidinecarboxylic acid, 2-methylpropyl ester

Product Description:

A potent inhibitor of acid ceramidase (IC50 = 12.8 nM for the human enzyme); inhibits acid ceramidase activity and increases levels of C16 dihydro ceramide and C16 ceramide in various melanoma cells; reduces growth of A375 and G361 melanoma cells (EC50s = 41.8 and 67.7 µM, respectively)

CAY24284-10 mg: ARN14988
CAY24284-10 mg: ARN14988